Hmmmm interesting. Funny you mention it because I was taking gaba not too long ago and it was in a mixture with some other stuff. Anyways, I think it was causing me to wake up kind of uncoordinated and feeling just kind of weird. Dissociative I guess you could say, which makes sense because it’s related to the NMDA receptors somehow I think. It supposedly “can’t” cross the blood brain barrier, at least this is repeated despite the fact that it can and does, it’s just an unreliable mechanism in which it does. Low levels of gaba were insinuated to absorb more in the brain also. I didn’t have this issue as if I took the full 750 mg I felt very strange consistently and none of the other supplements in the mixture would seem to do this.
There are, however, some foods where the caloric expenditure to process them is a little higher than the calories they provide the system. The clear example is water, especially ice-cold water. The body needs to warm it up before absorbing it, leading to a small caloric debt. Foods with very high water content, such as celery, also have this tiny catabolic effect. But the nutritional value of water and celery are not high enough to properly sustain an organism, so relying solely on these foods to lose weight can lead to serious health complications.
Since the benefits of exercise are virtually all hormonally mediated, it follows logically that manipulating levels of key hormones in the body can produce exaggerated responses to exercise. An example is the use of synthetic testosterone and growth hormone in athletes participating in sports that require a great deal of muscle mass, such as powerlifting, football and bodybuilding. On the other hand, the use of stimulants that mimic adrenalin, such as amphetamines, is prevalent in sports such as cycling and track, where muscle mass is not necessarily helpful or desirable, but the ability to maintain high levels of power output and energy expenditure is.