The study hypothesizes that a year of consecutive treatment with inhaled insulin compared to a placebo group receiving no insulin, will yield increased cognition, increased memory, and increased daily functioning. The study will look at biomarkers in cerebrospinal fluid, and will also measure brain atrophy before and after the study. It includes 240 people with Alzheimer’s disease. For six months prior to the placebo trial, participants will all be given inhaled insulin. By using intranasal insulin, researchers know that they can get insulin straight to the brain, where it may do some good for these study patients. 6
The presence of the isotope plutonium-240 in a sample limits its nuclear bomb potential, as plutonium-240 has a relatively high spontaneous fission rate (~440 fissions per second per gram—over 1,000 neutrons per second per gram),  raising the background neutron levels and thus increasing the risk of predetonation .  Plutonium is identified as either weapons-grade , fuel-grade, or reactor-grade based on the percentage of plutonium-240 that it contains. Weapons-grade plutonium contains less than 7% plutonium-240. Fuel-grade plutonium contains from 7% to less than 19%, and power reactor-grade contains 19% or more plutonium-240. Supergrade plutonium , with less than 4% of plutonium-240, is used in . Navy weapons stored in proximity to ship and submarine crews, due to its lower radioactivity.  The isotope plutonium-238 is not fissile but can undergo nuclear fission easily with fast neutrons as well as alpha decay.