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Antipsychotics are a class of drugs used commonly to treat psychotic disorders -- conditions in which thinking can be irrational, and people have false beliefs (delusions) or perceptions (hallucinations) -- and sometimes to treat mood disorders such as bipolar disorder or major depression. Different antipsychotics vary in their side effects, and some people have more trouble with certain side effects than with others. The doctor can change medications or dosages to help minimize unpleasant side effects. A drawback to some antipsychotic medications is their potential to cause sedation and problems with involuntary movements as well as weight gain and changes in blood sugar or cholesterol, which require periodic laboratory monitoring.