Nevoid hyperkeratosis of the nipple and/or areola treatment with topical steroid

A 15-year-old woman presented with a painless change of color and texture of her right breast areola. The lesion had started some months previously. An examination of her right breast showed a hyperpigmentation of the areola, which appeared thickened and verrucous (Fig, 1), Her right nipple and left breast showed no alteration. She gave no personal or family history of ichthyosis, epidermal nevi, ot acanthosis nigricans. She did not follow any phatmacologic treatment, Histologic examination of the lesion showed hyperkeratosis, acanthosis, and papillomatosis. Large keratin filled dilated ostia (Fig. 2) and filiform acanthosis resembling a delicate network (Fig, 3) were seen, Mammography and echography were normal. Topical application of retinoic acid was begun. An excellent cosmetic result was obtained after 1 month of daily application. The patient continues to use the topical retinoid acid intermittently. DISCUSSION Levy-FranckeP has classified hyperkeratosis of the nipples and areolae into three categories: Type I, hyperkeratosis of the nipple and areola represents the extension of a verrucous nevus. This type is usually unilateral. Type II, hyperkeratosis of nipple and areola associated with a disseminated dermatosis. This type may be bilateral. The nipple and areola may react strongly; then verrucous hyperkeratosis appears with an

Nevoid hyperkeratosis of the nipple and/or areola treatment with topical steroid

nevoid hyperkeratosis of the nipple and/or areola treatment with topical steroid

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nevoid hyperkeratosis of the nipple and/or areola treatment with topical steroidnevoid hyperkeratosis of the nipple and/or areola treatment with topical steroidnevoid hyperkeratosis of the nipple and/or areola treatment with topical steroidnevoid hyperkeratosis of the nipple and/or areola treatment with topical steroidnevoid hyperkeratosis of the nipple and/or areola treatment with topical steroid

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