Reversing steroid induced skin atrophy

Sugammadex has been shown to have affinity for two other aminosteroid neuromuscular blocking agents, vecuronium and pancuronium . Although sugammadex has a lower affinity for vecuronium than for rocuronium, reversal of vecuronium is still effective because fewer vecuronium molecules are present in vivo for equivalent blockade: vecuronium is approximately seven times more potent than rocuronium. Sugammadex encapsulates with a 1:1 ratio and therefore will adequately reverse vecuronium as there are fewer molecules to bind compared to rocuronium. [3] Shallow pancuronium blockade has been successfully reversed by sugammadex in phase III clinical trials. [4]

Reversing steroid induced skin atrophy

reversing steroid induced skin atrophy

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