Two heifers were implanted with 300 mg of the radiolabeled anabolic steroid, trenbolone acetate (TBA). After a 60 day slaughter and a 60 day removal followed by 76 day slaughter, total 3H-content in various tissues was --25 ng/g equivalents of TBA. Radioimmunoassay of the tissues showed that only 1--5% of the total residue present was TBA, its main metabolite trenbolone (TBOH), and TBOH glucuronide, plus up to 5% of other organic-soluble material. Of the radioactivity remaining about half was directly water-soluble, and the insoluble residue could be made water-soluble by treatment with the proteolytic enzymes pepsin and trypsin. These 2 portions were purified with Sephadex G-25 to give a low and high molecular weight fraction. Raney nickel reduction of sulfur bonds in either fraction released up to 50% of radioactivity into the organic phase. TLC showed that the latter contained 2 components which had characteristics similar to TBOH and its metabolites, and thus were at least partly drug-related metabolites. In vitro experiments with bovine liver also showed a small but definite protein binding. It is proposed that in dealing with these covalently bound residues, priority be given to the reactive drug intermediate and the type of binding to macromolecules rather than to the presence of the bound residue itself.
The result? Decreased libido, sperm production, fertility, and for some, impotence. Getting testosterone levels back to normal range can be difficult.
Trenorol Before & After Pictures Huge increase in muscle mass ★ ★ ★ ★ ★ Here’s a before and after from my 8 week cycle, I was using Trenorol along with a strict 60% carbs 40% protein diet. Rory C. VIEW REVIEW Lost 2% body fat & gained muscle ★ ★ ★ ★ ☆ I replaced my fat with muscle and gained 5 pounds. Body fat was around 12% and ended under 10%. I gained 30 pounds on my bench. Lucas D. VIEW REVIEW Gained 25 LB lean muscle ★ ★ ★ ★ ★ Gaining 13lbs in 4 weeks and staying lean while still getting stronger was something I’ve not done before! Cole W. VIEW REVIEW Lost 9% body fat ★ ★ ★ ★ ★ My body fat was just over 20% when I started I’m currently down to just over 11% and have gained weight. Jack M. VIEW REVIEW
Short & Long-Term Use of Trenbolone Acetate A drug doesn’t have to be used for a long period of time to cause long-term damage to organs and body system functions. The same applies to Trenbolone acetate.
Trenbolone acetate is a modified form of nandrolone.  The structure of trenbolone acetate is a 19-nor classification, which represents a structural change of the testosterone hormone. Trenbolone acetate lacks a carbon atom at the 19 position and carries a double bond at carbons 9 and 11. The position of these carbons slows its metabolism, which greatly increases its binding affinity to the AR, and inhibits it from undergoing aromatization into the corresponding estrogenic metabolite. Trenbolone acetate contains trenbolone modified with the addition of a carboxylic acid ester ( acetic acid ) at the 17β-hydroxyl group.  This facilitates the slow release of the AAS from the area of injection.